Table of Contents
1. The Market for Bio-Computing + Pharmaceuticals
1.1 Definition of Bio-Computing + Pharmaceutical Market
1.2 Bioscience Industry Facts That Impact Bio-computing
1.3 Bio-computing Opportunity Roadmap
1.4 Current Bio-Computing Market Participants
1.5 Bioscience Computing Infrastructure Requirements
1.6 Bio-Computing Technologies
1.6.1 Computer Infrastructure
1.6.2 Storage Network Infrastructure
1.6.3 Application Software
1.7 The Pharma Business
2. Drivers of Bio-Computing
2.1 Drivers of Bio-computing + Pharmaceuticals
2.1.1 Pharma Drug Discovery R&D
2.1.2 Rapid Pace of Scientific Developments
2.1.3 Current Computing Power is Affordable for Pharma R&D
2.1.4 Post Human Genome Project Era Databases
2.1.5 Computational Requirements for Structural and Functional
Proteomics R&D
2.1.6 Food Production Development
2.2 Commercial Applications
2.2.1 Genomic Databases2.2.2 Proteomic Databases
2.2.3 Applications
3. Case Studies in Bio-computing for Pharma R&D
3.1 Hardware Solutions
3.1.1 Agencourt Biosciences and Auspex Storage Solution
3.1.2 Bristol Myers Squibb, SGI and Incyte Genomics
3.1.3 Incyte Genomics and Red Hat Linux Compute Farm
3.1.4 National Cancer Institute and Genomics Pattern Matching
With Supercomputer
3.2.1 Celera Genomics, Blackstone Computing and Compaq Build
Massive Compute Solution
3.2.2 Hospital for Sick Children Genomic Database and IBM
Services3.2 Services Solutions3.3 Software Solutions
3.3.1 Aventis and In Silico Drug Discovery
3.3.2 Biogen, Inc. and Spotfire DecisionSite
3.3.3 Eli Lilly and Clinical Trial e-Business Patient Recruitment
3.3.4 Proctor and Gamble Pharmaceuticals and Phase Forward,
Inc. Clinical Trial Management
4. The Bio-Computing IT Market and Future Outlook
4.1 The Bio-Computing IT Market and Industry Segments
4.1.1 IT Services
4.1.2 Servers
4.1.3 Storage
4.1.4 Software
4.1.5 BioContent
4.2 Bio-Computing IT Market Size by Segment, 2001~2005
4.3 Total Size of the Bio-Computing IT Market
4.4 Forecast for Bio-computing R&D Market by Market Segments
4.4.1 The Bio-computing IT "Services' Market Segment
4.4.2 Forecast for the Bio-Computing 'Server' Market Segment
4.4.3 Forecast for the Bio-computing IT 'Storage' Market Segment
4.4.4 Forecast for the Bio-computing IT 'Software' Market
Segment
4.4.5 Forecast for the Bio-computing IT BioContent Market
Segment
4.4.6 Comparison of the Market Segment Forecasts
5. Future Directions in Bio-Computing
5.1 Overview of Past Trends
5.1.1 Recent Developments in Genomics That Impact on Bio-computing
5.1.2 Rapid Changes in Computer Systems
5.2 Indicators of Future Trends for Bio-Computing
5.2.1 Services
5.2.2 Software
5.2.2.1 Operating Systems
5.2.2.2 Applications
5.2.2.3 Tools for Computational Flexibility
5.2.3 Biocontent
5.2.4 Servers
5.2.5 Storage
6. Activities of Emerging Bio-Computing R&D IT Infrastructure
Firms
6.1 BioContent Providers
6.1.1 Celera Genomics Corporation
6.1.2 Human Genome Sciences, Inc.
6.1.3 Incyte Genomics, Inc.
6.1.4 NuTec Sciences, Inc., Life Science Div.
6.2 BioSoftware Application Providers
6.2.1 Accelrys, Inc. (subsidiary of Pharmacopeia Inc.)
6.2.2 Cellomics, Inc.6.2.3 InforMax, Inc.
6.2.4 Spotfire, Inc.
6.3 Hardware Systems Providers
6.3.1 Compaq Computer Corporation
6.3.2 IBM Corporation
6.3.3 Paracel, Inc.
6.4 Services Providers
6.4.1 Blackstone Computing
6.4.2 Entigen Corporation
6.4.3 Linux NetworX, Inc.
6.5 Systems Software Providers
6.5.1 Red Hat Linux, Inc.
6.5.2 TurboLinux, Inc.
7. Lessons Learned and Emerging Opportunities
7.1 Challenges of Drug Discovery R&D and Bio-computing
7.1.1 Science Bottlenecks Need to be Converted Computational
Problems 7.1.2 Genomics BioContent to Become a Commodity
7.2 Review of the Next Hot Development Areas in Bio-Computing7.2.1
More "Big Iron" in Bio-Computing7.2.2 Bio-Computing
in Clinical Trials
7.2.3 Personalized Medicine to Become a Theme7.3 Bio-Computing
Opportunities7.3.1 Role in Drug Discovery7.3.2 High Storage
Growth Ahead
7.3.3 Fast Growth Rates Expected for Consulting and e-Services
7.3.4 Software Opportunities
7.4 Summary
7.4.1 Vendors Need to Become Partners with Pharmas
7.4.2 Bio-computing to Increase Chances of Pharma Success
8. Appendix 1 Selection of Bio-computing Vendors
9. Appendix 2 Bioscience Glossary
List of Tables
T-1 Magnitude of Bio-computational Requirements
T-2 Computing Power Needed for Genomic & Protein R&D
T-3 Forecast for the Total Bio-computing IT Market, 2001-2005
T-4 Forecast for the Bio-computing IT 'Services' Market Segment,
2001-2005
T-5 Forecast for the Bio-computing IT 'Server' Market Segment,
2001-2005
T-6 Forecast for the Bio-computing IT 'Storage' Market Segment,
2001-2005
T-7 Forecast for the Bio-computing IT 'Software' Market Segment,
2001-2005
T-8 Forecast for the Bio-computing IT BioContent Market Segment,
2001-2005
T-9 Comparison of Forecasts for the Total Bio-computing IT
Market, 2001-2005
T-10 Selected Services Vendors
T-11 Selected Software Vendors
T-12 Selected BioContent VendorsT-13 Selected Server VendorsT-14
Selected Storage Vendors
List of Figures
F-1 Drug R&D Summary
F-2 Bio-Computing Opportunity Map
F-3 Bio-computing Vendor Market
F-4 Agencourt Biosciences and Network Storage Solution
F-5 Bristol-Myers Squibb and a Two Supercomputer Solution
F-6 Incyte Genomics and Linux Cluster Solution
F-7 Computer Model using PhysioLab Technology
F-8 The SpotFire DecisionSite User Interface
F-9 InForm Web-based Clinical Trial Management Screen
F-10 Forecast for Total Bio-computing IT Market, 2001-2005
F-11 Forecast for Bio-computing IT 'Services' Market Segment,
2001-2005
F-12 Forecast for Bio-computing IT 'Server' Market Segment,
2001-2005 62
F-13 Forecast for the Bio-computing IT 'Storage' Market Segment,
2001-2005
F-14 Forecast for Bio-computing IT 'Software' Market Segment,
2001-2005
F-15 Forecast for Bio-computing IT 'BioContent' Market Segment,
2001-2005
F-16 Comparison of Forecasts for the Total Bio-computing IT
Market, 2001-2005
F-17 Comparison of Segment Market Shares for the Bio-computing
IT Market, 2001 and 2005
F-18 Next Generation Scyld Beowulf cluster Computer
F-19 Big Pharma Drug Development Timeline
F-20 Drug Discovery Collaboration Map
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