Allergy Drug Pipeline and R&D 2009

Reports, MRG Multimedia Research Group, Inc.

Allergy Drug Pipeline and R&D 2009

Emerging Technologies, Companies, Products, Applications,

Sales & Market Share, and Worldwide Outlook

Published by MRG, Inc. and Fuji-Keizai
June 2009, 126 pages

Hard Copy Print Edition $995 USD
PDF Single-Departmental License $1,495 USD
PDF Corporate-Wide License $2,995 USD
California orders please add 9.25% sales tax

To order click here or contact Rob Smith at rsmith@mrgco.com

Executive Summary

This report describes current global research initiatives in the field of allergies. It focuses on the most common allergies, which affect more than 300 million persons worldwide: seasonal and perennial allergic rhinitis and food allergies.

Sales estimates from 2008 to 2013 are provided for the leading prescription allergy drugs and vaccines, as well as over-the-counter (OTC) allergy medicines in the U.S., European Union, Japan and rest of world area (defined as South America and the Caribbean, Middle East, Africa, and Asia except Japan). Forecasts include an analysis of the market forces affecting sales in each region, as well as a discussion of patent expirations of leading medications and the effects of generic competition on existing allergy drug sales.

Allergy medications and vaccines under development are discussed, with a comprehensive analysis of technology, stage of development and commercialization potential. This includes new molecular entities and indication expansions of medicines currently approved for other uses. For leading allergy drug candidates, sales estimates from 2009 to 2013 are provided.

Profiles of the 12 leading allergy drug developers offer details of these companies’ capabilities, particularly focusing on R&D strength, pipeline products, strategic alliances and partnerships, and the effects of any recent merger or acquisition activity. A directory of more than five dozen leading players worldwide allows readers to access companies’ own web sites for further review.

Information for this report was gathered from a wide variety of published sources; interviews with company representatives were then conducted to assess trends, and form the basis of the forecasting and competitive analysis.

This report is designed for business development and other senior executives, marketers, R&D managers, investors, VCs, consultants, entrepreneurs and others who require an in-depth understanding of the current status of the allergy therapeutics market and potential new products. More than 50 detailed tables or figures provide key data about items such as strategic alliances, M&As, market size, segments and the like.

Table of Contents

	Executive Summary

1	Overview of the Global Allergy Medications Market
1.1	Allergies as a Medical Condition
1.1.1	Types of Allergies
1.1.2	Signs and Symptoms
1.1.3	Physiological Response
1.1.4	Prevalence
1.2	Medical Treatment of Allergies
1.2.1	Prescription Medications: Current Usage & Unmet Needs
1.2.1.1	U.S.
1.2.1.2	Europe
1.2.1.3	Japan
1.2.1.4	ROW
1.2.2	Non-Prescription Products: Current Usage & Unmet Needs
1.2.2.1	U.S.
1.2.2.2	Europe
1.2.2.3	Japan
1.2.2.4	ROW

2	Global Allergy Medications Market Forecast 2008-2013
2.1	Rx Allergy Medications Market
2.1.1	Rx Allergy Drug Market Forecast by Product
2.1.1.1	Growth Drivers
2.1.1.2	Market Restraints
2.1.2	Rx Allergy Drug Market Forecast by Region
2.1.3	Rx Allergy Drug Market Forecast by Product Class
2.2	OTC Allergy Drug Market
2.2.1	OTC Allergy Drug Market Forecast by Product
2.2.2	Growth Drivers
2.2.3	Market Restraints
2.2.4	OTC Allergy Drug Market Forecast by Region
2.2.5	OTC Allergy Drug Market Forecast by Product Class
2.3	Rx & OTC Allergy Drug Market
2.3.1	Rx & OTC Allergy Drug Market Forecast by Leading Manufacturers
2.3.2	Rx & OTC Allergy Drug Market Share of Leading Drug Manufacturers

3	Allergy Drug Development: New Molecular Entities
3.1	All Allergy Drug Developers Position
3.1.1	Challenges in Allergy Drug Development
3.2	Key Products Under Development
3.2.1	Antihistamines
3.2.1.1	Physiology and Mechanism of Action
3.2.1.2	Leading Antihistamine Allergy Drug Candidates
3.2.2	Corticosteroids
3.2.2.1	Physiology and Mechanism of Action
3.2.2.2	Leading Corticosteroid Allergy Drug Candidates
3.2.3	Mast Cell Inhibitors
3.2.3.1	Physiology and Mechanism of Action
3.2.3.2	Leading Mast Cell Inhibitor Allergy Drug Candidates
3.2.4	Allergy Immunotherapy
3.2.4.1	Physiology and Mechanism of Action
3.2.4.2	Leading Immunotherapy Allergy Drug Candidates
3.2.5	Vaccines
3.2.5.1	Physiology and Mechanism of Action
3.2.5.2	Leading Allergy Vaccine Candidates
3.2.6	Other Types of Allergy Drugs
3.2.6.1	Physiology and Mechanism of Action
3.2.6.2	Other Leading Allergy Candidates
3.3	Global Market Forecast for New Allergy Drugs, 2008-2013
3.3.1	New Allergy Drug Market Forecast: Total and Segment Market
3.3.2	Growth Drivers
3.3.2.1	The Importance of Patents
3.3.3	Market Restraints

4	Allergy Drug Development: Indication Expansion
4.1	Indication Expansion for New Usage
4.1.1	The Economic Benefits of Indication Expansion
4.1.2	Challenges in Allergy Drug Indication Expansion
4.2	Key Products Under Development
4.2.1	Database of Allergy Indication Expansion Initiatives by Company
4.2.2	Leading Areas of R&D Activity
4.2.2.1	Clarinex
4.2.2.2	Nasonex
4.2.2.3	Patanase
4.2.2.4	Singulair
4.2.2.5	Veramyst
4.2.2.6	Xolair
4.2.2.7	Xyzal
4.3	Global Market Forecast for Allergy Drug Indication Expansions
4.3.1	Growth Drivers
4.3.2	Market Restraints

5	Allergy Drug Development: Basic Research
5.1	Basic Research Group & Activity
5.1.1	Challenges in Basic Allergy Research
5.2	Key Areas of Investigation
5.2	Unanswered Questions

6	Strategic Alliances for Allergy Drug Development
6.1	Types of Strategic Alliances
6.2	Current Strategic Alliances for Allergy Drug Development

7	Activities of the Leading Allergy Drug Developers Common Research Items: 1) Product Profile 2) R&D Strength and Capabilities 3) Marketed Allergy Drugs 4) Allergy Drug Pipeline 5) Profile
7.1	Alcon Research
7.2	Allergy Therapeutics
7.3	AstraZeneca
7.4	GlaxoSmithKline
7.5	Johnson & Johnson
7.6	Meda AB
7.7	Merck
7.8	Novartis
7.9	Sanofi-Aventis
7.10	Schering-Plough
7.11	Sepracor
7.12	UCB Pharma

8	Total Allergy Drug Market: Forecasts & Directions

9	Other Top Companies with Allergy Projects

10	Database of Allergy Drug Developers

Table of Figures

Figure 2-1:	Rx Allergy Drug Market Product Segments Share, 2008
Figure 2-2:	Rx Allergy Drug Market Product Segments Share, 2013
Figure 2-3:	Rx & OTC Market Shares of Top Allergy Drug Manufacturers, 2008
Figure 2-4:	Rx & OTC Market Shares of Top Allergy Drug Manufacturers, 2013
Figure 3-1:	Allergy Compounds Tested by Phase of Development
Figure 3-2:	The Role of Mast Cells in Allergy Response
Figure 3-3:	Production of TH2 Cytokines
Figure 3-4:	Market Shares of New Allergy Drugs by Segment, 2013
Figure 4-1:	Cost and Time Savings of Indication Expansions
Figure 4-2:	Product Market Share of Allergy Drug Indication Expansions, 2009
Figure 4-3:	Product Market Share of Allergy Drug Indication Expansions, 2013
Figure 5-1:	National Institutes of Health Research Budget by Disease Area, Fiscal 2008
Figure 6-1:	Comparison of Selected Deal Types
Figure 8-1:	Total Allergy Drug Sales Growth by Segment, 2008-2013
Figure 8-2:	Allergy Drug Market Share by Segment, 2008
Figure 8-3:	Allergy Drug Market Share by Segment, 2013

Table of Tables

Table 1-1:	Gell & Coombs Classification of Allergic Reactions
Table 1-2:	Global Prevalence of Allergies
Table 1-3:	Leading Prescription Allergy Medications
Table 1-4:	U.S. DTC Advertising for Leading Rx and OTC Allergy Medications 2008
Table 1-5:	Leading OTC Allergy Medications
Table 2-1:	Rx Allergy Drug Market Forecast 2008-2013 by Product in $Million
Table 2-2:	U.S. Patent Expirations of Leading Prescription Allergy Drugs
Table 2-3:	Rx Allergy Drug Market Forecast, 2008-2013 by Region in $Million
Table 2-4:	Rx Allergy Drug Market Forecast, 2008-2013 by Product Class in $Million
Table 2-5:	Rx Allergy Drug Market Product Segments Share, 2008 vs. 2013
Table 2-6:	OTC Allergy Drug Market Forecast, 2008-2013 by Product in $Million
Table 2-7:	OTC Allergy Drug Market Forecast, 2008-2013 by Region in $Million
Table 2-8:	OTC Allergy Drug Market Forecast, 2008-2013 by Product Class in $Million
Table 2-9:	Rx & OTC Allergy Drug* Sales of Leading Manufacturers, 2008-2013 in $Million
Table 2-10:	Rx & OTC Market Shares of Leading Allergy Drug Manufacturers, 2008 vs. 2013
Table 3-1:	Key Characteristics of NMEs, Generics and Indication Expansions
Table 3-2:	All Allergy Drug Developers Product Position Overview
Table 3-3:	Antihistamine Developers Product Position
Table 3-4:	Corticosteroid Developers Product Position
Table 3-5:	Mast Cell Inhibitors Developers Product Position
Table 3-6:	Immunotherapy Developers Product Position
Table 3-7:	Vaccine Developers Product Position
Table 3-8:	Other Allergy Drug Developers Product Position
Table 3-9:	Sales of New Allergy Drugs by Segment, 2008-2013
Table 4-1:	Selected Recent Allergy Drug Indication Expansions, U.S.
Table 4-2:	U.S. R&D Expenditure for New Medicines by the Pharma-Industry
Table 4-3:	Selected Allergy Drug Indication Expansion Trials
Table 4-4:	Sales of Allergy Drug Indication Expansions, 2008-2013 in $Millions
Table 4-5:	Product Market Share of Allergy Drug Indication Expansions, 2009 vs. 2013
Table 5-1:	Leading Organizations & Details for Basic Allergy Research
Table 5-2:	Recent Basic Research in the Field of Allergies
Table 6-1:	Ongoing Strategic Alliances for Allergy Drug Development
Table 7-1:	Major Allergy Drug Developers' Activities
Table 8-1:	Total Allergy Drug Sales by Segment, 2008-2013 in $Million
Table 9-1:	Other Top Companies with Late Stage Allergy Projects
Table 9-2:	Other Top Companies with Early Stage Allergy Projects

Allergy Drug Pipeline and R&D 2009: Emerging Technologies, Companies, Products, Applications, Sales & Market Share, and Worldwide Outlook (June 2009) is 126 pages. Hard copy edition for $995.00 USD, a PDF single-departmental license for $1,495.00 USD, and a pdf corporate license for $2,995.00. For more information or to order the report, contact Rob Smith at 1-408-453-5553 or rsmith@mrgco.com.

Order Form